(Photo credit: Kamil Krzaczynski-USA TODAY Sports)

Michael Wacha pitched seven scoreless innings in his final start of the season, and Jurickson Profar notched a season-high four RBIs as the San Diego Padres cruised to a 6-1 win over the host Chicago White Sox on Saturday night.

Ji Man Choi and Juan Soto added one RBI apiece for San Diego (81-80), which won its fourth game in a row. Ha-Seong Kim went 4-for-5, scored a run and stole two bases.

Lenyn Sosa hit a solo homer to provide the lone run for Chicago (61-100). The White Sox reached triple digits in losses for only the fifth time in franchise history.

Wacha (14-4) scattered three hits, walked one and struck out seven to notch his third victory in a row. He lowered his ERA from 3.39 to 3.22 to finish the season.

White Sox right-hander Mike Clevinger (9-9) gave up six runs, all of which were earned, on seven hits in 1 2/3 innings. His ERA climbed from 3.40 to 3.77.

San Diego jumped to a 4-0 lead in the top of the first inning.

Profar stepped to the plate with the bases loaded and one out, and cleared the bases with a double to right field. Moments later, Profar advanced to third base on a wild pitch by Clevinger and came home to score on a double by Choi.

The Padres' barrage against Clevinger continued with two more runs in the second.

Soto drove in the first run of the inning with a double to right that scored Xander Bogaerts. Profar added a run-scoring single for his fourth RBI of the game.

Chicago got on the scoreboard in the eighth. Sosa hit a 373-foot shot to right field for his sixth homer in 51 games this season.

After Clevinger departed, the White Sox bullpen combined for 7 1/3 scoreless innings. Tanner Banks handled 2 1/3 innings, Sammy Peralta pitched 1 2/3 innings, Luis Patino tossed 2 1/3 innings and Bryan Shaw tossed the final frame.